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Review
. 2014 Jun;28(3):187-92.
doi: 10.1016/j.apnu.2014.01.004. Epub 2014 Feb 5.

Gender differences in factors associated with delirium severity in older adults with dementia

Ann M Kolanowski  1 , Nikki L Hill  2 , Esra Kurum  3 , Donna M Fick  4 , Andrea M Yevchak  5 , Paula Mulhall  6 , Linda Clare  7 , Michael Valenzuela  8
Affiliations
Review

Gender differences in factors associated with delirium severity in older adults with dementia

Ann M Kolanowski et al. Arch Psychiatr Nurs. 2014 Jun.

Abstract

The purpose of this descriptive correlational study was to explore potential gender differences in the relationship of dementia severity, age, APOE status, cognitive reserve and co-morbidity (two potentially modifiable factors), to delirium severity in older adults. Baseline data from an ongoing clinical trial and a Poisson regression procedure were used in the analyses. Participants were 148 elderly individuals with dementia and delirium admitted to post-acute care. In women, delirium severity was related to dementia severity (p=0.002) and co-morbidity moderated that effect (p=0.03). In men, education was marginally associated with delirium severity (p=0.06). Implications for research are discussed.

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Figures

Figure 1
Figure 1
Interaction Effect of Co-morbidity and Dementia Severity on Delirium Severity.
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References

    1. Adamis D, Treloar A, Martin FC, Gregson N, Hamilton G, Macdonald AJD. APOE and cytokines as biological markers for recovery of prevalent delirium in elderly medical inpatients. International Journal of Geriatric Psychiatry. 2007;22(7):688–694. doi: 10.1002/gps.1732. - DOI - PubMed
    1. Barnes LL, Wilson RS, Bienias JL, Schneiger JA, Evans DA, Bennett DA. Sex Differences in the Clinical Manifestations of Alzheimer disease Pathology. Archives of General Psychiatry. 2005;62(6):685–691. doi: 10.1001/archpsyc.62.6.685. - DOI - PubMed
    1. Bee Gek Tay L, Chew Chan MP, Sian Chong M. Functional improvement in hospitalized older adults is independent of dementia diagnosis: Experience of a specialized delirium management unit. Journal of Hospital Medicine. 2013;8(6):321–327. doi: 10.1002/jhm.2035. - DOI - PubMed
    1. Bennett DA, Wilson RS, Schneiger JA, Evans DA, Mendes de Leon CF, Arnold SE, Bienias JL. Education Modifies the Relation of AD Pathology to Level of Cognitive Function in Older Persons. Neurology. 2003;60(12):1909–1915. - PubMed
    1. Blessed G, Tomlinson BE, Roth M. The Association between Quantitative Measures of Dementia and of Senile Change in the Cerebral Grey Matter of Elderly Subjects. British Journal of Psychiatry. 1968;114(512):797–811. - PubMed

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