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. 2014 Apr;36(2):129-33.
doi: 10.4103/0253-7176.130968.

A controlled study of serum lipid profiles in Indian patients with depressive episode

Bichitra Nanda Patra  1 , Sudhir K Khandelwal  1 , Rakesh K Chadda  1 , Lakshmy Ramakrishnan  2
Affiliations

A controlled study of serum lipid profiles in Indian patients with depressive episode

Bichitra Nanda Patra et al. Indian J Psychol Med. 2014 Apr.

Abstract

Background: Lower levels of circulating lipid fractions and cholesterol are risk factors for impulsivity and depressive disorder. A lower level of serum cholesterol is also associated with patients presenting with history of self-harm.

Materials and methods: A total of 30 depressive patients and 30 healthy matched control subjects were recruited from the department of Psychiatry of a tertiary care hospital. We measured serum total cholesterol (TC), low-density lipoprotein (LDL) and high-density lipoprotein cholesterol and triglyceride levels of both patient and control group.

Results: The serum TC and LDL-cholesterol levels were found to be significantly lower in study group than that of control group.

Conclusion: Lower levels of serum cholesterol are associated with depressive disorder.

Keywords: Body mass-index; depression; self-harm; serum cholesterol; serum lipid profiles; suicide.

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Conflict of interest statement

Conflict of Interest: None.

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