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Case Reports
. 1989 Feb;9(1):48-51.

Autoinduction of hypertensive reactions by tranylcypromine?

P E Keck Jr  1 , H G Pope Jr, A A Nierenberg
Affiliations
  • PMID: 2486182
Case Reports

Autoinduction of hypertensive reactions by tranylcypromine?

P E Keck Jr et al. J Clin Psychopharmacol. 1989 Feb.

Abstract

Although rarely described in the psychiatric literature, patients treated with monoamine oxidase inhibitors may experience acute hypertensive reactions that are not readily attributable to dietary indiscretion or use of concomitant medications. Four cases of apparent autoinduction of hypertensive reactions in patients receiving tranylcypromine are presented. The mechanism of this reaction is unknown, but may involve conversion of tranylcypromine to metabolites with pressor activity.

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