The tale of 2 trials: disentangling contradictory evidence on hypertonic saline for acute bronchiolitis

Affiliations

¹ Division of Pediatric Emergency Medicine, Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
² Translating Emergency Knowledge for Kids, Manitoba Institute of Child Health, University of Manitoba, Winnipeg, Manitoba, Canada3Department of Pediatrics, University of Manitoba, Winnipeg, Manitoba, Canada.

Editorial

Sim Grewal et al. JAMA Pediatr. 2014 Jul.

. 2014 Jul;168(7):607-9.

doi: 10.1001/jamapediatrics.2014.423.

¹ Division of Pediatric Emergency Medicine, Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
² Translating Emergency Knowledge for Kids, Manitoba Institute of Child Health, University of Manitoba, Winnipeg, Manitoba, Canada3Department of Pediatrics, University of Manitoba, Winnipeg, Manitoba, Canada.

No abstract available

Comment in

A Living Systematic Review of Nebulized Hypertonic Saline for Acute Bronchiolitis in Infants.
Badgett RG, Vindhyal M, Stirnaman JT, Gibson CM, Halaby R. Badgett RG, et al. JAMA Pediatr. 2015 Aug;169(8):788-9. doi: 10.1001/jamapediatrics.2015.0681. JAMA Pediatr. 2015. PMID: 26099054 No abstract available.

Nebulized hypertonic saline for bronchiolitis in the emergency department: a randomized clinical trial.
Florin TA, Shaw KN, Kittick M, Yakscoe S, Zorc JJ. Florin TA, et al. JAMA Pediatr. 2014 Jul;168(7):664-70. doi: 10.1001/jamapediatrics.2013.5306. JAMA Pediatr. 2014. PMID: 24862342 Clinical Trial.
Nebulized hypertonic saline for bronchiolitis: a randomized clinical trial.
Wu S, Baker C, Lang ME, Schrager SM, Liley FF, Papa C, Mira V, Balkian A, Mason WH. Wu S, et al. JAMA Pediatr. 2014 Jul;168(7):657-63. doi: 10.1001/jamapediatrics.2014.301. JAMA Pediatr. 2014. PMID: 24862623 Clinical Trial.