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Randomized Controlled Trial
. 2014:2014:197216.
doi: 10.1155/2014/197216. Epub 2014 Apr 17.

Lifestyle intervention involving calorie restriction with or without aerobic exercise training improves liver fat in adults with visceral adiposity

Eiichi Yoshimura  1 , Hideaki Kumahara  2 , Takuro Tobina  3 , Takuro Matsuda  4 , Makoto Ayabe  5 , Akira Kiyonaga  4 , Keizo Anzai  6 , Yasuki Higaki  4 , Hiroaki Tanaka  7
Affiliations
Randomized Controlled Trial

Lifestyle intervention involving calorie restriction with or without aerobic exercise training improves liver fat in adults with visceral adiposity

Eiichi Yoshimura et al. J Obes. 2014.

Abstract

Objective: To evaluate the effect of calorie restriction-induced weight loss with or without aerobic exercise on liver fat.

Methods: Thirty-three adults with visceral adiposity were divided into calorie restriction (CR; n = 18) or CR and aerobic exercise (CR + Ex; n = 15) groups. Target energy intake was 25 kcal/kg of ideal body weight. The CR + Ex group had a targeted exercise time of 300 min/wk or more at lactate threshold intensity for 12 weeks.

Results: Reductions in body weight (CR, -5.3 ± 0.8 kg; CR + Ex, -5.1 ± 0.7 kg), fat mass (CR, -4.9 ± 0.9 kg; CR + Ex, -4.4 ± 0.6 kg), and visceral fat (CR, -24 ± 5 cm2; CR + Ex, -37 ± 5 cm2) were not statistically different between groups. Liver fat decreased significantly in both groups, with no difference between groups. Change in maximal oxygen uptake was significantly greater in the CR + Ex group than in the CR group (CR, -0.7 ± 0.7 mL/kg/min; CR + Ex, 2.9 ± 1.0 mL/kg/min).

Conclusion: Both CR and CR + Ex resulted in an improved reduction in liver fat; however, there was no additive effect of exercise training.

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Flow of participants through the study.
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