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. 2014 Jun;20(6):976-82.
doi: 10.3201/eid2006.131770.

High prevalence of Ancylostoma ceylanicum hookworm infections in humans, Cambodia, 2012

Tawin Inpankaew, Fabian Schär, Anders Dalsgaard, Virak Khieu, Wissanuwat Chimnoi, Chamnan Chhoun, Daream Sok, Hanspeter Marti, Sinuon Muth, Peter Odermatt, Rebecca J Traub

High prevalence of Ancylostoma ceylanicum hookworm infections in humans, Cambodia, 2012

Tawin Inpankaew et al. Emerg Infect Dis. 2014 Jun.

Abstract

Ancylostoma ceylanicum, a hookworm of canids and felids in Asia, is becoming the second most common hookworm infecting humans. In 2012, we investigated the prevalence and infection dynamics of and risk factors for hookworm infections in humans and dogs in a rural Cambodian village. Over 57% of the population was infected with hookworms; of those, 52% harbored A. ceylanicum hookworms. The greatest intensities of A. ceylanicum eggs were in persons 21-30 years of age. Over 90% of dogs also harbored A. ceylanicum hookworms. Characterization of the cytochrome oxidase-1 gene divided isolates of A. ceylanicum hookworms into 2 groups, 1 containing isolates from humans only and the other a mix of isolates from humans and animals. We hypothesize that preventative chemotherapy in the absence of concurrent hygiene and animal health programs may be a factor leading to emergence of A. ceylanicum infections; thus, we advocate for a One Health approach to control this zoonosis.

Keywords: Ancylostoma ceylanicum; Cambodia; hookworm; humans; zoonosis.

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Figures

Figure
Figure
Prevalence and intensity (eggs per gram) of Necator americanus and Ancylostoma ceylanicum hookworm infections in humans of different ages in rural Dong village, Rovieng District, Preah Vihear Province, Cambodia, 2012.
See this image and copyright information in PMC

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