Exploring new models of easiRNA biogenesis
- PMID: 24866189
- DOI: 10.1038/ng.2993
Exploring new models of easiRNA biogenesis
Abstract
Although silent transposons in plants can be reactivated by stress or during development, their potential deleterious effects are prevented by transposon-derived epigenetically activated small interfering RNAs (easiRNAs). A new study shows how serendipitous interactions between reactivated transposons and endogenous microRNAs might initiate easiRNA biogenesis, establishing an unexpected link between these two classes of silencing small RNAs.
Comment on
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miRNAs trigger widespread epigenetically activated siRNAs from transposons in Arabidopsis.Nature. 2014 Apr 17;508(7496):411-5. doi: 10.1038/nature13069. Epub 2014 Mar 16. Nature. 2014. PMID: 24670663 Free PMC article.
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