Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Jun;133(6):828e-834e.
doi: 10.1097/PRS.0000000000000221.

Examining factors associated with oral health-related quality of life for youth with cleft

Affiliations

Examining factors associated with oral health-related quality of life for youth with cleft

Hillary L Broder et al. Plast Reconstr Surg. 2014 Jun.

Abstract

Background: Patient-reported quality-of-life outcomes in cleft lip-cleft palate treatment are critical for evidence-based care. Scant data exist analyzing treatment from the patient's perspective. The authors examined the interrelationship among variables associated with oral health-related quality of life among youth with cleft.

Methods: As part of an ongoing longitudinal study, clinical evaluations and research questionnaire packets were completed before surgical recommendations were made (baseline). Participants completed the Child Oral Health Impact Profile, a validated oral health-related quality-of-life measure for children with cleft. During the baseline clinical evaluations, plastic surgeons determined whether surgical interventions were recommended within the year (expert determination represents a greater degree of current clinical need). General linear models incorporating surgical recommendation, gender, and age were fit for each subscale of and for the total Child Oral Health Impact Profile. Significant interaction terms were evaluated for their effect on the subscale.

Results: Baseline assessments were obtained from 1200 participants (mean, 11.8 years; 57 percent male). Participants with a surgical recommendation had lower quality of life on all but the self-esteem subscale compared with those without a surgical recommendation (p < 0.002). Two subscales had statistically significant age-sex interactions (p < 0.003), whereas another subscale had a statistically significant surgery by sex interaction term (p = 0.027).

Conclusions: Overall, youth for whom surgery is currently recommended had lower oral health-related quality-of-life scores on the Child Oral Health Impact Profile Total scale than those with no surgical recommendation; older female subjects had lower quality-of-life scores than male subjects.

Clinical question/level of evidence: Risk, II.

PubMed Disclaimer

References

    1. Parker SE, Mai CT, Canfield MA, Rickard R, Wang Y, Meyer RE, et al. Updated National Birth Prevalence Estimates for Selected Birth Defects in the United States, 2004-2006. Birth Defects Research Part a-Clinical and Molecular Teratology. 2010;88(12):1008–1016. - PubMed
    1. Dixon MJ, Marazita ML, Beaty TH, Murray JC. Cleft lip and palate: understanding genetic and environmental influences. Nature Reviews Genetics. 2011;12(3):167–178. - PMC - PubMed
    1. Klassen AF, Tsangaris E, Forrest CR, Wong KWY, Pusic AL, Cano SJ, et al. Quality of life of children treated for cleft lip and/or palate: A systematic review. Journal of Plastic Reconstructive and Aesthetic Surgery. 2012;65(5):547–557. - PubMed
    1. Patrick DL, Topolski TD, Edwards TC, Aspinall CL, Kapp-Simon KA, Rumsey NJ, et al. Measuring the quality of life of youth with facial differences. Cleft Palate-Craniofacial Journal. 2007;44(5):538–47. - PubMed
    1. Broder HL, Wilson-Genderson M. Reliability and convergent and discriminant validity of the Child Oral Health Impact Profile (COHIP Child's version). Community Dent Oral Epidemiol. 2007;35(Suppl 1):20–31. - PubMed

Publication types