[Effect of hypophysin and desoxycorticosterone-21-acetate on renal function in calves in the neonatal period. II. Urinary excretion of electrolytes]

Abstract

Clearance experiments concerning the influence of hypophysin + (0.1 vol. unit/kg) and desoxycorticosterone-21-acetate (0.1 mg/kg) on sodium, potassium, calcium, magnesium and inorganic phosphorus excretion in urine have been carried out on 12 bulls at the age of 2-5 weeks of life. After hypophysin injection kidney purification of sodium, potassium and chloride ions has been noticed and hypophysin effect on tubular absorption processes turned out to be clearly late in relation to its influence on glomerular filtration decrease. After desoxycorticosterone-21-acetate injection, lowering of clearances of both sodium and potassium has been noticed and it may prove that kidney mechanisms responsible for potassium ion regulation show functional immaturity. Hypophysin and desoxycorticosterone-21-acetate in calves at the age 2-5 weeks have not affected kidney processes of calcium, magnesium and inorganic phosphorus excretion in urine.