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Case Reports
. 2014 Mar;18(2):240-3.
doi: 10.4103/0972-124X.131341.

Central odontogenic fibroma

Sanjay Venugopal  1 , Satish Radhakrishna  2 , Akshatha Raj  1 , Anshul Sawhney  1
Affiliations
Case Reports

Central odontogenic fibroma

Sanjay Venugopal et al. J Indian Soc Periodontol. 2014 Mar.

Abstract

Central odontogenic fibroma (COF), which has been categorized under the subheading of odontogenic tumors of ectomesenchyme, is such an uncommon neoplasm that much of its nature is left uncharted. COF is a rare tumor that accounts for 0.1% of all odontogenic tumors. Clinically, the lesion grows slowly and leads to cortical expansion. Radiologically, the lesion may be unilocular or multilocular. In some cases, it may be associated with root resorption or displacement. Histopathologically, the lesion is characterized by mature collagen fibers and numerous fibroblasts. A case of COF of the mandible in a male patient aged 49 years is described in this report. The patient showed no symptoms, no history of swelling discomfort or pain, and was unaware of the presence of the lesion. Orthopantomogram (OPG) showed generalized bone loss along with a unilocular radiolucent area, with a clear sclerotic lining and angular bone loss. Surgical enucleation of the lesion along with placement of osseo-graft, which is a bioresorbable demineralized bone matrix (DMBM), and platelet-rich fibrin was carried out in the defect site. Following surgery, patient was recalled for revaluation of the lesion; the surgical site showed good healing and an increase in bone height was seen.

Keywords: Central odontogenic fibroma; neoplasms; odontogenic tumors.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Preoperative photograph
Figure 2
Figure 2
Orthopantomogram showing generalized bone loss along with unilocular radiolucent area resembling a “tear drop shape” involving mandibular left premolar and the mesial root of mandibular first molar
Figure 3
Figure 3
Incision
Figure 4
Figure 4
Flap raised
Figure 5
Figure 5
Surgical window
Figure 6
Figure 6
Enucleation of lesion
Figure 7
Figure 7
Intravenous blood drawn
Figure 8
Figure 8
Centrifugation
Figure 9
Figure 9
Platelet-rich fibrin
Figure 10
Figure 10
Fibrin clot
Figure 11
Figure 11
Fibrin clot mixed with osseo-graft demineralized bone matrix
Figure 12
Figure 12
Sutures placed
Figure 13
Figure 13
Postoperative radiograph after 5 months
Figure 14
Figure 14
Histopathology
See this image and copyright information in PMC

References

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