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Clinical Trial
. 1989 Apr;3(2):199-202.
doi: 10.1007/BF01883865.

Peripheral hemodynamic effects of ibopamine in patients with congestive heart failure. A placebo-controlled, double-blind study

C Longhini  1 , L Ansani, G F Musacci, S Aggio, E Baracca, T Toselli, P Ghirardi
Affiliations
Clinical Trial

Peripheral hemodynamic effects of ibopamine in patients with congestive heart failure. A placebo-controlled, double-blind study

C Longhini et al. Cardiovasc Drugs Ther. 1989 Apr.

Abstract

Under double-blind conditions, 150 mg of ibopamine (di-isobutyric ester of N-methyldopamine) or placebo were given orally to 11 patients with congestive heart failure; after 3 hours, 50 mg of sulpiride were administered intramuscularly. Peripheral hemodynamics were evaluated at the level of the forearm using strain-gauge plethysmography. Ibopamine increased arterial blood flow and venous capacity and decreased arterial peripheral resistance; these effects were counteracted by sulpiride. No significant changes were observed after placebo and sulpiride. These findings confirm the vasodilating effects of ibopamine on peripheral hemodynamics and its utility in patients for the treatment of congestive heart failure.

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References

    1. Eur J Clin Pharmacol. 1983;24(5):585-9 - PubMed
    1. Arzneimittelforschung. 1986 Dec;36(12):1829-34 - PubMed
    1. J Cardiovasc Pharmacol. 1984 Sep-Oct;6(5):748-55 - PubMed
    1. Circulation. 1986 Apr;73(4):740-8 - PubMed
    1. Angiology. 1964 Jul;15:293-304 - PubMed

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