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. 2014 May;8(3):609-14.
doi: 10.1177/1932296814528134. Epub 2014 Apr 2.

Self-monitoring of blood glucose: a prerequisite for diabetes management in outcome trials

Oliver Schnell  1 , Markolf Hanefeld  2 , Louis Monnier  3
Affiliations

Self-monitoring of blood glucose: a prerequisite for diabetes management in outcome trials

Oliver Schnell et al. J Diabetes Sci Technol. 2014 May.

Abstract

Evidence for the value of self-monitoring of blood glucose (SMBG) with regard to the achievement of treatment targets, detection of postprandial glucose excursions, and minimization of glycemic variability is increasing. In large clinical trials, SMBG is a key component for the optimization of diabetes treatment in insulin-treated diabetes. It also plays an essential role in outcome studies. However, details of SMBG use in both the methods and results sections of clinical articles are frequently scarce. Also, a discussion of the SMBG data and its impact on insulin therapy is valuable. In the recently completed Outcome Reduction with an Initial Glargine INtervention (ORIGIN) trial, SMBG was described in detail and insulin titration was largely driven by SMBG. Both aspects largely contributed to the fact that near-normal control was achieved over a long-term period.

Keywords: SMBG; blood glucose; diabetes; self-monitoring.

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Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: Markolf Hanefeld has received speaker honoraria from Takeda, GSK, Roche, BAYER, Lilly, and Sanofi-Aventis, and advisory board honoraria from Sanofi-Aventis, Takeda, BMS, and GSK.

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