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. 2014 May 30;9(5):e97527.
doi: 10.1371/journal.pone.0097527. eCollection 2014.

HIV incidence and risk factors in Chinese young men who have sex with men--a prospective cohort study

Zhenxin Dong  1 , Jie Xu  2 , Hongbo Zhang  1 , Zhi Dou  2 , Guodong Mi  2 , Yuhua Ruan  2 , Limei Shen  3 , Xiangdong Min  4 , Guanghua Lan  5 , Fan Li  6 , Tian Li  7 , Zhen Ning  8 , Guohui Wu  9 , Min She  1 , Zunyou Wu  2 ; China National HIV Prevention Study Group
Collaborators, Affiliations

HIV incidence and risk factors in Chinese young men who have sex with men--a prospective cohort study

Zhenxin Dong et al. PLoS One. .

Abstract

Objectives: To assess HIV incidence and its associated risk factors among young men who have sex with men (YMSM) in urban areas, China.

Design: The study used a prospective cohort study design and standard diagnostic tests.

Methods: A twelve-month prospective cohort study was conducted among YMSM (18-25 years old) in 8 large cities in China. The participants were recruited via snowball sampling. A total of 1102 HIV-negative YMSM completed baseline assessment, 878 YMSM participants completed 6-month follow-up, and 902 completed 12-month follow-up. HIV was screened by an enzyme-linked immunosorbent assay and confirmed with Western Blot. Syphilis was screened via rapid plasma reagent and confirmed by treponema pallidum particle agglutination assay.

Results: 78 HIV seroconversions were identified within 1168.4 person-year observations yielding an incidence rate of 6.7 per 100 person-years. HIV seroconversion was associated with non-student status (RR = 2.61, 90% CI = 1.3-5.26), low HIV transmission knowledge (RR = 8.87, 90% CI = 2.16-36.43), and syphilis infection (RR = 5.04, 90% CI = 2.57-9.90).

Conclusions: Incidence of HIV among YMSM is high in urban areas of China. Interventions measures are required to contain the HIV epidemic within this population.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

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