Colonoscopic evaluation in ulcerative colitis
- PMID: 24879406
- PMCID: PMC4124270
- DOI: 10.1093/gastro/gou028
Colonoscopic evaluation in ulcerative colitis
Abstract
Colonoscopic evaluation is an important tool in the evaluation of ulcerative colitis (UC). UC is divided by disease extent into proctitis, proctosigmoiditis, left-sided colitis, and pan-colitis. In addition, a cecal or peri-appendiceal patch and backwash ileitis are associated with UC. The extent and behavior of UC has been characterized further using various indices and scoring systems; among these systems is the Mayo Score, which is widely used in current clinical trials for new medications. As these medical therapies for UC have developed, achieving mucosal healing with medications has become an important therapeutic objective.
Keywords: colonoscopic evaluation; disease activity; mucosal healing; ulcerative colitis.
© The Author(s) 2014. Published by Oxford University Press and the Digestive Science Publishing Co. Limited.
Figures
Similar articles
-
Clinical Significance of Isolated Peri-Appendiceal Lesions in Patients With Left Sided Ulcerative Colitis.Gastroenterology Res. 2011 Apr;4(2):58-63. doi: 10.4021/gr302w. Epub 2011 Mar 20. Gastroenterology Res. 2011. PMID: 27942315 Free PMC article.
-
Fecal calprotectin and ulcerative colitis endoscopic activity index as indicators of mucosal healing in ulcerative colitis.Intern Emerg Med. 2015 Apr;10(3):321-8. doi: 10.1007/s11739-014-1144-x. Epub 2014 Nov 4. Intern Emerg Med. 2015. PMID: 25366383
-
Pathologic features and clinical significance of "backwash" ileitis in ulcerative colitis.Am J Surg Pathol. 2005 Nov;29(11):1472-81. doi: 10.1097/01.pas.0000176435.19197.88. Am J Surg Pathol. 2005. PMID: 16224214
-
Medical management of ulcerative proctitis, proctosigmoiditis, and left-sided colitis.Semin Gastrointest Dis. 2001 Oct;12(4):263-74. Semin Gastrointest Dis. 2001. PMID: 11726080 Review.
-
A comprehensive review and update on ulcerative colitis.Dis Mon. 2019 Dec;65(12):100851. doi: 10.1016/j.disamonth.2019.02.004. Epub 2019 Mar 2. Dis Mon. 2019. PMID: 30837080 Review.
Cited by
-
Artificial Intelligence in Gastrointestinal Endoscopy.Clin Endosc. 2020 Mar;53(2):132-141. doi: 10.5946/ce.2020.038. Epub 2020 Mar 30. Clin Endosc. 2020. PMID: 32252506 Free PMC article.
-
Ulcerative Colitis: Shifting Sands.Drugs R D. 2019 Jun;19(2):227-234. doi: 10.1007/s40268-019-0263-2. Drugs R D. 2019. PMID: 30827006 Free PMC article. Review.
-
Fatigue in Patients with Newly Diagnosed Inflammatory Bowel Disease: Results from a Prospective Inception Cohort, the IBSEN III Study.J Crohns Colitis. 2023 Nov 24;17(11):1781-1790. doi: 10.1093/ecco-jcc/jjad094. J Crohns Colitis. 2023. PMID: 37279652 Free PMC article.
-
Ratio of Circulating Estrogen Receptors Beta and Alpha (ERβ/ERα) Indicates Endoscopic Activity in Patients with Crohn's Disease.Dig Dis Sci. 2017 Oct;62(10):2744-2754. doi: 10.1007/s10620-017-4717-5. Epub 2017 Aug 19. Dig Dis Sci. 2017. PMID: 28823012
-
Relating the molecular phenotype of ulcerative colitis to the clinical course.Sci Rep. 2025 Mar 11;15(1):8342. doi: 10.1038/s41598-025-90618-8. Sci Rep. 2025. PMID: 40064933 Free PMC article.
References
-
- Ordas I, Eckmann L, Talamini M, et al. Ulcerative colitis. Lancet. 2012;380:1606–19. - PubMed
-
- Langan RC, Gotsch PB, Krafczyk MA, et al. Ulcerative colitis: diagnosis and treatment. Am Fam Physician. 2007;76:1323–30. - PubMed
-
- Leighton JA, Shen B, Baron TH, et al. ASGE guideline: endoscopy in the diagnosis and treatment of inflammatory bowel disease. Gastrointest Endosc. 2006;63:558–65. - PubMed
-
- Magro F, Rodrigues A, Vieira AI, et al. Review of the disease course among adult ulcerative colitis population-based longitudinal cohorts. Inflamm Bowel Dis. 2012;18:573–83. - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources
Research Materials