Alveolar graft in the cleft lip and palate patient: review of 104 cases
- PMID: 24880440
- PMCID: PMC4192580
- DOI: 10.4317/medoral.19413
Alveolar graft in the cleft lip and palate patient: review of 104 cases
Abstract
Introduction: Alveolar bone grafting is a vital part of the rehabilitation of cleft patients. The factors that have been most frequently associated with the success of the graft are the age at grafting and the pre-grafting orthodontic treatment.
Objectives: 1) Describe the cases of alveolar bone grafts performed at the Maxilofacial Unit of Hospital Sant Joan de Déu, Barcelona (HSJD); and 2) Analyze the success/failure of alveolar grafts and related variables.
Material and methods: Descriptive retrospective study using a sample of 104 patients who underwent a secondary alveolar graft at the Craniofacial Unit of HSJD between 1998 and 2012. The graft was done by the same surgeon in all patients using bone from the iliac crest.
Results: 70% of the patients underwent the procedure before the age of 15 (median 14.45 years); 70% of the graft patients underwent pre-graft maxillary expansion. A total of 100 cases were recorded as successful (median age of 14.58 years, 68 underwent pre-graft expansion) and only 4 were recorded as failures (median age of 17.62 years, 3 underwent pre-graft expansion). We did not find statistically significant differences in age at the time of grafting or pre-surgical expansion when comparing the success and failure groups. We found the success rate of the graft to be 96.2%.
Conclusions: The number of failures was too small to establish a statistically significant conclusion in our sample regarding the age at grafting and pre-grafting expansion. The use of alveolar bone grafting from the iliac crest has a very high success rate with a very low incidence of complications. Existing controversies regarding secondary bone grafting and the wide range of success rates found in the literature suggest that it is necessary to establish a specific treatment protocol that ensures the success of this procedure.
Figures



Similar articles
-
A Comparative Analysis of Recombinant Human Bone Morphogenetic Protein-2 with a Demineralized Bone Matrix versus Iliac Crest Bone Graft for Secondary Alveolar Bone Grafts in Patients with Cleft Lip and Palate: Review of 501 Cases.Plast Reconstr Surg. 2017 Aug;140(2):318e-325e. doi: 10.1097/PRS.0000000000003519. Plast Reconstr Surg. 2017. PMID: 28746285
-
Secondary Alveolar Bone Grafting (CLEFTSiS) 2007-2010.Cleft Palate Craniofac J. 2016 Mar;53(2):141-6. doi: 10.1597/14-093.1. Cleft Palate Craniofac J. 2016. PMID: 26914161
-
Cranial bone grafting for alveolar clefts: a 25-year review of outcomes.Plast Reconstr Surg. 2014 May;133(5):662e-668e. doi: 10.1097/PRS.0000000000000109. Plast Reconstr Surg. 2014. PMID: 24776568
-
Secondary alveolar bone grafting using autologous versus alloplastic material in the treatment of cleft lip and palate patients: systematic review and meta-analysis.Prog Orthod. 2019 Feb 11;20(1):6. doi: 10.1186/s40510-018-0252-y. Prog Orthod. 2019. PMID: 30740615 Free PMC article.
-
Orthodontic Preparation for Secondary Alveolar Bone Grafting in Patients with Complete Cleft Lip and Palate.Oral Maxillofac Surg Clin North Am. 2020 May;32(2):205-217. doi: 10.1016/j.coms.2020.01.003. Epub 2020 Feb 22. Oral Maxillofac Surg Clin North Am. 2020. PMID: 32098718 Review.
Cited by
-
Functional stability analyses of maxillofacial skeleton bearing cleft deformities.Sci Rep. 2019 Mar 12;9(1):4261. doi: 10.1038/s41598-019-40478-w. Sci Rep. 2019. PMID: 30862870 Free PMC article.
-
Rapid Maxillary Expansion Treatment in Patients with Cleft Lip and Palate: A Survey on Clinical Experience in the European Cleft Centers.J Clin Med. 2023 Apr 27;12(9):3159. doi: 10.3390/jcm12093159. J Clin Med. 2023. PMID: 37176600 Free PMC article.
-
Alveolar cleft reconstruction using autogenous double iliac corticocancellous bone blocks technique versus particulate autogenous spongy bone graft from anterior iliac crest.Clin Oral Investig. 2025 Apr 15;29(5):248. doi: 10.1007/s00784-025-06288-3. Clin Oral Investig. 2025. PMID: 40229452 Free PMC article. Clinical Trial.
-
Enhanced Osteogenesis Potential of MG-63 Cells through Sustained Delivery of VEGF via Liposomal Hydrogel.Gels. 2023 Jul 10;9(7):562. doi: 10.3390/gels9070562. Gels. 2023. PMID: 37504441 Free PMC article.
-
Evaluation of alveolar bone support around incisors in patients with unilateral cleft lip, alveolus, and palate in late mixed dentition using cone beam computed tomography.Angle Orthod. 2018 May;88(3):299-305. doi: 10.2319/071517-472.1. Epub 2018 Jan 31. Angle Orthod. 2018. PMID: 29384701 Free PMC article.
References
-
- Guo J. Injertos óseos secundarios para la hendidura alveolar en ni-os con labio leporino o labio leporino y fisura palatine. Cochrane Database of Systematic Reviews. 2011;6:CD008050. - PubMed
-
- Miller LL, Kauffmann D, St John D, Wang D, Grant JH3rd, Waite PD. Retrospective Review of 99 patients with secondary alveolar cleft repair. J Oral Maxillofac Surg. 2010;68:1283–1289. - PubMed
-
- Bajaj A, Wongworawat A, Punjabi A. Management of Alveolar Clefts. J Craniof Surg. 2003;14:840–846. - PubMed
-
- Long RE, Spangler BE, Yow M. Cleft width and secondary bone graft success. CleftPalateCraniofac J. 1995;32:420–427. - PubMed
-
- Lilja J. Alveolar Bonegrafting. Indian J Plast urg. 2009;42:110–115. - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical