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Randomized Controlled Trial
. 2014 Sep 1;19(5):e518-24.
doi: 10.4317/medoral.19511.

Effect of Erythrinamu lungu on anxiety during extraction of third molars

Maria-Luisa Silveira-Souto  1 , Carla-Rocha São-Mateus, Liane-Maciel de Almeida-Souza, Francisco-Carlos Groppo
Affiliations
Randomized Controlled Trial

Effect of Erythrinamu lungu on anxiety during extraction of third molars

Maria-Luisa Silveira-Souto et al. Med Oral Patol Oral Cir Bucal. .

Abstract

Objectives: The aim of the present study was to evaluate the effect of Erythrinamu lungu on the control of dental anxiety in patients who had under gone bilateral extraction of asymptomatic, impacted mandibular third molars.

Material and methods: In a randomized, double-blind, crossover study, 30 healthy volunteers (5 men and 25 women, over 18 years of age), received either 500mg of E.mulungu (MulunguMatusa®) or 500 mg of placebo, p.o., one hour before surgical procedure. The level ofanxiety was assessed through questionnaire sand physical parameters, such as blood pressure, heart rate andoxygen saturation. Data were analyzed by Chi-square test, ANOVA (Tukey test) and Friedman with significance level of 5%.

Results: A higher preference (Chi-square, p = 0.0062) for E. mulungu was observed for both genders. Volunteers with higher anxiety levels tended to to prefer E. mulungu. No statistically significant differences were verified in blood pressure (one-way ANOVA, p = 0.1259), heart rate (Friedman, p> 0.05) and oxygen saturation (Friedman, p = 0.7664) among periods and types of treatments.

Conclusions: E. mulungu showed an anxiolytic effect without significant changes in physiological parameters. It could be considered as an alternative to control the anxiety in adult patients undergoing mandibular thirdmolars surgery.

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Conflict of interest statement

Conflict of interest statement:We declare that there is no conflict of interest in this manuscript. There is not any financial and personal relationships with other people or organisations that could inappropriately influence our work. There is an attached file with the signatures.

Figures

Figure 1
Figure 1
Mean (standard deviation) of systolic and diastolic blood pressure.
Figure 2
Figure 2
Median (interquartile range) of the heart rate.
Figure 3
Figure 3
Median (interquartile range) of SpO2.
See this image and copyright information in PMC

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