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Meta-Analysis
. 2014 Sep;39(8):866-86.
doi: 10.1093/jpepsy/jsu032. Epub 2014 May 30.

Systematic review and meta-analysis of parent and family-based interventions for children and adolescents with chronic medical conditions

Emily F Law  1 , Emma Fisher  2 , Jessica Fales  2 , Melanie Noel  2 , Christopher Eccleston  2
Affiliations
Meta-Analysis

Systematic review and meta-analysis of parent and family-based interventions for children and adolescents with chronic medical conditions

Emily F Law et al. J Pediatr Psychol. 2014 Sep.

Abstract

Objective: To quantify the effects of parent- and family-based psychological therapies for youth with common chronic medical conditions on parent and family outcomes (primary aim) and child outcomes (secondary aim).

Methods: MEDLINE, EMBASE, and PsycINFO were searched from inception to April 2013. 37 randomized controlled trials were included. Quality of the evidence was evaluated using GRADE criteria. Data were extracted on parent, family, and child outcomes.

Results: Pooled psychological therapies had a positive effect on parent behavior at posttreatment and follow-up; no significant improvement was observed for other outcome domains. Problem-solving therapy (PST) improved parent mental health and parent behavior at posttreatment and follow-up. There was insufficient evidence to evaluate cognitive-behavioral and systems therapies for many outcome domains.

Conclusions: Parent- and family-based psychological therapies can improve parent outcomes, with PST emerging as particularly promising. Future research should incorporate consensus statements for outcomes assessment, multisite recruitment, and active comparator conditions.

Keywords: asthma; cancer; cardiovascular disease; children; chronic illness; chronic pain; cystic fibrosis; diabetes mellitus; epilepsy; family; meta-analysis; parent; psychological therapies; randomized controlled trials; solid organ transplant; spina bifida; systematic review; traumatic brain injury.

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Figures

Figure 1.
Figure 1.
PRISMA flow diagram.
Figure 2.
Figure 2.
Summary of risk of bias ratings.
Figure 3.
Figure 3.
Significant improvement in parent behavior at posttreatment across all therapy types.
Figure 4.
Figure 4.
Significant improvement in parent behavior at follow-up across all therapy types.
See this image and copyright information in PMC

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