Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Sep;211(3):208-214.e1.
doi: 10.1016/j.ajog.2014.05.040. Epub 2014 May 29.

Developing a systematic approach to safer medication use during pregnancy: summary of a Centers for Disease Control and Prevention--convened meeting

Cheryl S Broussard  1 , Meghan T Frey  2 , Sonia Hernandez-Diaz  3 , Michael F Greene  4 , Christina D Chambers  5 , Leyla Sahin  6 , Beth A Collins Sharp  7 , Margaret A Honein  8
Affiliations

Developing a systematic approach to safer medication use during pregnancy: summary of a Centers for Disease Control and Prevention--convened meeting

Cheryl S Broussard et al. Am J Obstet Gynecol. 2014 Sep.

Abstract

To address information gaps that limit informed clinical decisions on medication use in pregnancy, the Centers for Disease Control and Prevention (CDC) solicited expert input on a draft prototype outlining a systematic approach to evaluating the quality and strength of existing evidence for associated risks. The draft prototype outlined a process for the systematic review of available evidence and deliberations by a panel of experts to inform clinical decision making for managing health conditions in pregnancy. At an expert meeting convened by the CDC in January 2013, participants divided into working groups discussed decision points within the prototype. This report summarizes their discussions of best practices for formulating an expert review process, developing evidence summaries and treatment guidance, and disseminating information. There is clear recognition of current knowledge gaps and a strong collaboration of federal partners, academic experts, and professional organizations willing to work together toward safer medication use during pregnancy.

Keywords: Centers for Disease Control and Prevention; expert review; medications; pregnancy; teratogens.

PubMed Disclaimer

Figures

FIGURE
FIGURE. Proposed flow diagram of expert review panel model
Broussard. A systematic approach to safer medication use during pregnancy. Am J Obstet Gynecol 2014.
See this image and copyright information in PMC

Comment in

  • Getting to safer and smarter medication use during pregnancy.
    Umans JG, Lindheimer MD. Umans JG, et al. Am J Obstet Gynecol. 2015 Jul;213(1):115-116. doi: 10.1016/j.ajog.2014.12.035. Epub 2014 Dec 30. Am J Obstet Gynecol. 2015. PMID: 25555661 No abstract available.
  • Reply: To PMID 24881821.
    Broussard CS, Sahin L, Tassinari MS. Broussard CS, et al. Am J Obstet Gynecol. 2015 Jul;213(1):116. doi: 10.1016/j.ajog.2014.12.036. Epub 2014 Dec 31. Am J Obstet Gynecol. 2015. PMID: 25557207 Free PMC article. No abstract available.

References

    1. Centers for Disease Control and Prevention Treating for two: safer medication use in pregnancy. Available at: http://www.cdc.gov/treatingfortwo. Accessed March 26, 2014.
    1. Mitchell AA, Gilboa SM, Werler MM, et al. Medication use during pregnancy, with particular focus on prescription drugs: 1976-2008. Am J Obstet Gynecol. 2011;205:51.e1–8. - PMC - PubMed
    1. Adam MP, Polifka JE, Friedman JM. Evolving knowledge of the teratogenicity of medications in human pregnancy. Am J Med Genet C Semin Med Genet. 2011;157:175–82. - PubMed
    1. Lagoy CT, Joshi N, Cragan JD, et al. Medication use during pregnancy and lactation: an urgent call for public health action. J Womens Health. 2005;14:104–9. - PubMed
    1. Fitzpatrick RB. REPROTOX: an information system on environmental hazards to human reproduction and development. Med Ref Serv Q. 2008;27:73–80. - PubMed

Publication types