Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2013 Apr;7(2):246-250.
doi: 10.4103/1305-7456.110198.

Chemoprevention of premalignant and malignant lesions of oral cavity: Recent trends

Ashish S Bodhade  1 , Alka M Dive  1
Affiliations
Review

Chemoprevention of premalignant and malignant lesions of oral cavity: Recent trends

Ashish S Bodhade et al. Eur J Dent. 2013 Apr.

Abstract

The word chemoprevention includes prevention of initiation, promotion, and progression of carcinogenesis to cancer. This article is an attempt to review the dietary chemopreventive agents and their mode of action in chemoprevention of oral premalignant lesions and oral cancer using a systematic approach. Selected chemoprevention trials are discussed with a focus on strategies of trial design and clinical outcome. Future in the field of chemoprevention will be more promising than the recently available therapeutic alternatives.

Keywords: Antioxidants; dietary chemopreventive agents; head and neck malignancy; premalignant lesions.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: None declared

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Theisen C. Chemoprevention: What's in a Name? J Natl Cancer Inst. 2001;93:743. - PubMed
    1. Jordan VC. Estrogen, selective estrogen receptor modulation, and coronary heart disease: Something or nothing. J Natl Cancer Inst. 2001;93:2–4. - PubMed
    1. Mehrotra R, Pandya S, Chaudhary AK, Kumar M, Singh M. Prevalence of oral pre-malignant and malignant lesions at a Tertiary Level Hospital in Allahabad, India. Asian Pac J Cancer Prev. 2008;9:263–5. - PubMed
    1. Wattenberg LW. Inhibition of Carcinogenesis by Minor Dietary Constituents. Cancer Res. 1992;52:2085s–91. - PubMed
    1. Li Y, Wicha MS, Schwartz SJ, Sun D. Implications of cancer stem cell theory for cancer chemoprevention by natural dietary compounds. J Nutr Biochem. 2011;22:799–806. - PMC - PubMed