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. 2014 May 21:12:159.
doi: 10.1186/1477-7819-12-159.

Histopathological evaluation of non-melanoma skin cancer

Ali Koyuncuer  1
Affiliations

Histopathological evaluation of non-melanoma skin cancer

Ali Koyuncuer. World J Surg Oncol. .

Abstract

Background: Non-melanoma skin cancers (NMSCs) are the most frequently seen cancers worldwide.

Methods: The medical records of patients diagnosed with basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) in Hatay Antakya pathology laboratory between January 2010 and September 2012 were retrospectively included in the study. Tumors were categorized according to age, gender, anatomical localization, type, solitary-multiplicity, tumor diameter (0 to 2 mm, 2.1 to 6 mm and >6.1 mm), and presence of ulceration (BCCs), and morphological subtype, histopatological features and grades (SCCs).

Results: A total of 136 tumors in 127 NMSC cases were examined. Solitary tumors were seen in 118 (92.9%), and multiple tumors in 9 (7.1%) patients. Mean age of the patients was 68.5 ± 13 years. BCC was observed in 96 (75.6%) and SCC in 31 (24.4%) patients. Mean diameter of all types of solitary and multiple tumors was 7.42 ± 3.49 mm. Nodular subtype focal cystic changes were observed in 49 (47.6%) patients. All tumors (solitary and multiple) were seen on the face (67.6%), scalp (11.8%), and ear (11%). Well differentiated SCCs were detected in 20 cases (64.5%); ulceration was observed in 58.1% of all tumors.

Conclusions: Epidemiologic and histopathological investigations, routine skin scanning performed on the elderly population and dermatological examination will help to improve efficient health applications.

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Figures

Figure 1
Figure 1
Morphological subtypes of basal cell carcinomas (BCCs) and their anatomic locations.
Figure 2
Figure 2
Basal cell carcinoma of the nodular (solid) type, with cystic change present. (Hematoxylin and eosin, x200).
Figure 3
Figure 3
Squamous cell carcinoma, well differentiated, shows keratocysts. (Hematoxylin and eosin, x200).
See this image and copyright information in PMC

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