Fine needle cytology--is aspiration suction necessary? A study of 100 masses in various sites

Abstract

One hundred consecutive superficial mass lesions in various body sites were sampled by both conventional fine needle aspiration (FNA) and by a fine needle without the application of syringe suction. The latter technique is based on the principle of capillarity and may be termed "fine needle capillary" (FNC) sampling. The two sampling techniques were compared using five objective parameters: (1) the amount of diagnostic cellular material present, (2) the retention of appropriate architecture and cellular arrangement, (3) the degree of cellular degeneration, (4) the cellular trauma and (5) the volume of obscuring background blood and clots. There was no statistically significant difference between the efficacies of the two sampling techniques for any of the parameters studied. FNA sampling was diagnostic in a greater number of cases than was FNC sampling, but this difference was not statistically significant at a level of P = .05. When FNC sampling was diagnostic, it more frequently produced superior-quality material; conventional FNA, although diagnostic in a greater number of cases, mostly produced adequate, rather than superior-quality, material. This trend was not, however, statistically significant at a level of P = .05. These findings differ from those of previous studies (which have shown overall superiority of FNC sampling over conventional FNA sampling) and suggest that the technique of fine needle sampling employed for cytodiagnosis can be left to the personal preference of the operator.