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Comment
. 2014 Jun 24;111(25):E2512-3.
doi: 10.1073/pnas.1406554111. Epub 2014 Jun 2.

Anti-HIV drug particles may overcome lymphatic drug insufficiency and associated HIV persistence

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Comment

Anti-HIV drug particles may overcome lymphatic drug insufficiency and associated HIV persistence

Jennifer P Freeling et al. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The authors declare no conflict of interest.

Comment on

References

    1. Fletcher CV, et al. Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues. Proc Natl Acad Sci USA. 2014;111(6):2307–2312. - PMC - PubMed
    1. Kinman L, et al. Lipid-drug association enhanced HIV-1 protease inhibitor indinavir localization in lymphoid tissues and viral load reduction: A proof of concept study in HIV-2287–infected macaques. J Acquir Immune Defic Syndr. 2003;34(4):387–397. - PubMed
    1. Heath TJ, Kerlin RL, Spalding HJ. Afferent pathways of lymph flow within the popliteal node in sheep. J Anat. 1986;149:65–75. - PMC - PubMed
    1. Kinman L, et al. Optimization of lipid-indinavir complexes for localization in lymphoid tissues of HIV-infected macaques. J Acquir Immune Defic Syndr. 2006;42(2):155–161. - PubMed
    1. Bui T, et al. Novel Gd nanoparticles enhance vascular contrast for high-resolution magnetic resonance imaging. PLoS ONE. 2010;5(9):e13082. - PMC - PubMed

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