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. 2014 Jul;32(3):335-44, viii.
doi: 10.1016/j.det.2014.03.010.

Actinic prurigo

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Actinic prurigo

Martha C Valbuena et al. Dermatol Clin. 2014 Jul.

Abstract

Actinic prurigo is a chronic photodermatosis with onset in childhood or before 20 years of age. It is most prevalent in Amerindians and Latin American mestizos, although it has been reported worldwide. Patients present with photodistributed, erythematous excoriated papules, cheilitis, and conjunctivitis. There is strong association with human leukocyte antigen DR4, especially the DRB1*0407 subtype. Treatment consists of photoprotection and the use of thalidomide.

Keywords: Actinic prurigo; Human leukocyte antigen; Polymorphic light eruption; Thalidomide.

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