Actinic prurigo
- PMID: 24891055
- DOI: 10.1016/j.det.2014.03.010
Actinic prurigo
Abstract
Actinic prurigo is a chronic photodermatosis with onset in childhood or before 20 years of age. It is most prevalent in Amerindians and Latin American mestizos, although it has been reported worldwide. Patients present with photodistributed, erythematous excoriated papules, cheilitis, and conjunctivitis. There is strong association with human leukocyte antigen DR4, especially the DRB1*0407 subtype. Treatment consists of photoprotection and the use of thalidomide.
Keywords: Actinic prurigo; Human leukocyte antigen; Polymorphic light eruption; Thalidomide.
Copyright © 2014 Elsevier Inc. All rights reserved.
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