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Case Reports
. 2014 Jul;91(1):84-5.
doi: 10.4269/ajtmh.14-0058. Epub 2014 Jun 2.

Trypanosoma cruzi meningoencephalitis in a patient with acquired immunodeficiency syndrome

Kosuke Yasukawa  1 , Shital M Patel  2 , Charlene A Flash  2 , Charles E Stager  2 , Jerry C Goodman  2 , Laila Woc-Colburn  2
Affiliations
Case Reports

Trypanosoma cruzi meningoencephalitis in a patient with acquired immunodeficiency syndrome

Kosuke Yasukawa et al. Am J Trop Med Hyg. 2014 Jul.

Abstract

As a result of global migration, a significant number of people with Trypanosoma cruzi infection now live in the United States, Canada, many countries in Europe, and other non-endemic countries. Trypanosoma cruzi meningoencephalitis is a rare cause of ring-enhancing lesions in patients with acquired immunodeficiency syndrome (AIDS) that can closely mimic central nervous system (CNS) toxoplasmosis. We report a case of CNS Chagas reactivation in an AIDS patient successfully treated with benznidazole and antiretroviral therapy in the United States.

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Figures

Figure 1.
Figure 1.
Trypanosoma cruzi trypomastigotes in cerebrospinal fluid (CSF) (Giemsa stain, ×1,000).
Figure 2.
Figure 2.
Trypanosoma cruzi amastigotes with rod-shaped kinetoplasts in glial cells (Giemsa stain, ×1,000).
See this image and copyright information in PMC

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