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. 2014 Apr;56(2):188-90.
doi: 10.4103/0019-5545.130506.

A case of psychosis due to Fahr's syndrome and response to behavioral disturbances with risperidone and oxcarbazepine

Affiliations

A case of psychosis due to Fahr's syndrome and response to behavioral disturbances with risperidone and oxcarbazepine

Abhijeet Dhawalram Faye et al. Indian J Psychiatry. 2014 Apr.

Abstract

Calcification of basal ganglia or Fahr's syndrome is a rare disease characterized by bilateral and symmetrical intracranial deposition of calcium mainly in cerebral basal ganglia. Motor and neuropsychiatric symptoms are prominent features. We report a case presented with a few motor symptoms, features of delirium and prominent psychiatric symptoms (disorganized behavior) predominantly evident after the improvement in delirium. Radiological findings were suggestive of bilateral basal ganglia calcification. Parathyroid hormone levels were low with no significant findings in other investigations and negative family history. Patient showed significant improvement in behavioral disturbances with risperidone, low dose of lorazepam, oxcarbazepine, and memantine.

Keywords: Basal ganglia; Fahr's syndrome; calcification; parathyroid hormone; psychiatric symptoms.

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Conflict of interest statement

Conflict of Interest: None declared

Figures

Figure 1
Figure 1
Computed tomography section of the patient showing calcification in Basal ganglia region

References

    1. Srivastava S, Bhatia MS, Sharma V, Mahajan S, Rajender G. Fahr's disease: An incidental finding in a case presenting with psychosis. Ger J Psychiatry. 2010;13:86–90.
    1. Benke T, Karner E, Seppi K, Delazer M, Marksteiner J, Donnemiller E. Subacute dementia and imaging correlates in a case of Fahr's disease. J Neurol Neurosurg Psychiatry. 2004;75:1163–5. - PMC - PubMed
    1. Trautner RJ, Cummings JL, Read SL, Benson DF. Idiopathic basal ganglia calcification and organic mood disorder. Am J Psychiatry. 1988;145:350–3. - PubMed
    1. Beall SS, Patten BM, Mallette L, Jankovic J. Abnormal systemic metabolism of iron, porphyrin, and calcium in Fahr's syndrome. Ann Neurol. 1989;26:569–75. - PubMed
    1. Bonazza S, La Morgia C, Martinelli P, Capellari S. Strio-pallido-dentate calcinosis: A diagnostic approach in adult patients. Neurol Sci. 2011;32:537–45. - PubMed