A correlation between the levels of phenobarbital, phenytoin and valproic acid in the blood serum and in saliva from children treated due to epilepsy
- PMID: 2489248
Item in Clipboard
A correlation between the levels of phenobarbital, phenytoin and valproic acid in the blood serum and in saliva from children treated due to epilepsy
Mater Med Pol.
1989 Oct-Dec.
Abstract
Blood serum and saliva levels of phenobarbital, phenytoin and valproic acid were estimated in children treated due to epilepsy. The ratio between the levels of the above drugs in saliva and blood serum can be of importance in calculating approximated levels of the drugs without a need of inconvenient inserting of needle and taking blood in children.
Similar articles
-
[A study on cerebrospinal fluid and saliva to serum concentration ratios of anticonvulsants--Phenytoin, Phenobarbital, Valproic Acid and Primidone in epileptic patients].Seishin Shinkeigaku Zasshi. 1982;84(9):661-79. Seishin Shinkeigaku Zasshi. 1982. PMID: 6820506 Japanese. No abstract available.
-
[Measurement of the blood concentration of antiepileptic drugs. II Special cases].Nouv Presse Med. 1975 May 24;4(21):1573-6. Nouv Presse Med. 1975. PMID: 765962 French. No abstract available.
-
Predictability of unbound antiepileptic drug concentrations in children treated with valproic acid and phenytoin.Clin Pharm. 1988 Sep;7(9):688-93. Clin Pharm. 1988. PMID: 3149223 No abstract available.
-
[Valproic acid in the treatment of epilepsy with special emphasis on serum level determination (author's transl)].Fortschr Neurol Psychiatr Grenzgeb. 1978 Jun;46(6):327-41. Fortschr Neurol Psychiatr Grenzgeb. 1978. PMID: 352872 Review. German.
-
Rational use of antiepileptic drug levels.Pharmacol Ther. 1992;54(3):297-305. doi: 10.1016/0163-7258(92)90004-j. Pharmacol Ther. 1992. PMID: 1465479 Review.
Cited by
-
Therapeutic drug concentration monitoring using saliva samples. Focus on anticonvulsants.Clin Pharmacokinet. 1999 Jun;36(6):453-70. doi: 10.2165/00003088-199936060-00006. Clin Pharmacokinet. 1999. PMID: 10427469 Review.