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Randomized Controlled Trial
. 2014 Sep;40(9):1295-302.
doi: 10.1007/s00134-014-3339-z. Epub 2014 Jun 4.

A randomized clinical trial of an intervention to relieve thirst and dry mouth in intensive care unit patients

Kathleen Puntillo  1 , Shoshana R Arai, Bruce A Cooper, Nancy A Stotts, Judith E Nelson
Affiliations
Randomized Controlled Trial

A randomized clinical trial of an intervention to relieve thirst and dry mouth in intensive care unit patients

Kathleen Puntillo et al. Intensive Care Med. 2014 Sep.

Abstract

Purpose: To test an intervention bundle for thirst intensity, thirst distress, and dry mouth, which are among the most pervasive, intense, distressful, unrecognized, and undertreated symptoms in ICU patients, but for which data-based interventions are lacking.

Methods: This was a single-blinded randomized clinical trial in three ICUs in a tertiary medical center in urban California. A total of 252 cognitively intact patients reporting thirst intensity (TI) and/or thirst distress (TD) scores ≥3 on 0-10 numeric rating scales (NRS) were randomized to intervention or usual care groups. A research team nurse (RTN#1) obtained patients' pre-procedure TI and TD scores and reports of dry mouth. She then administered a thirst bundle to the intervention group: oral swab wipes, sterile ice-cold water sprays, and a lip moisturizer, or observed patients in the usual care group. RTN#2, blinded to group assignment, obtained post-procedure TI and TD scores. Up to six sessions per patient were conducted across 2 days.

Results: Multilevel linear regression determined that the average decreases in TI and TD scores from pre-procedure to post-procedure were significantly greater in the intervention group (2.3 and 1.8 NRS points, respectively) versus the usual care group (0.6 and 0.4 points, respectively) (p < 0.05). The usual care group was 1.9 times more likely than the intervention group to report dry mouth for each additional session on day 1.

Conclusion: This simple, inexpensive thirst bundle significantly decreased ICU patients' thirst and dry mouth and can be considered a practice intervention for patients experiencing thirst.

Trial registration: ClinicalTrials.gov NCT01015755.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1. Consolidated Standards of Reporting Trials (CONSORT)-style Flow Diagram of Screening,a Recruitment, and Randomization
aA total of 1417 patients were screened for thirst intensity and/or distress. b Thirst intensity and/or distress ≥ 3 on 0 – 10 numeric rating scale. c Data from all patients used in analyses.
See this image and copyright information in PMC

Comment in

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