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. 2014 Jun;3(6):175-82.
doi: 10.1302/2046-3758.36.2000239.

Mortality after total hip replacement surgery: A systematic review

J R Berstock  1 , A D Beswick  1 , E Lenguerrand  1 , M R Whitehouse  1 , A W Blom  1
Affiliations

Mortality after total hip replacement surgery: A systematic review

J R Berstock et al. Bone Joint Res. 2014 Jun.

Abstract

Total hip replacement causes a short-term increase in the risk of mortality. It is important to quantify this and to identify modifiable risk factors so that the risk of post-operative mortality can be minimised. We performed a systematic review and critical evaluation of the current literature on the topic. We identified 32 studies published over the last 10 years which provide either 30-day or 90-day mortality data. We estimate the pooled incidence of mortality during the first 30 and 90 days following hip replacement to be 0.30% (95% CI 0.22 to 0.38) and 0.65% (95% CI 0.50 to 0.81), respectively. We found strong evidence of a temporal trend towards reducing mortality rates despite increasingly co-morbid patients. The risk factors for early mortality most commonly identified are increasing age, male gender and co-morbid conditions, particularly cardiovascular disease. Cardiovascular complications appear to have overtaken fatal pulmonary emboli as the leading cause of death after hip replacement. Cite this article: Bone Joint Res 2014;3:175-82.

Keywords: Hip arthroplasty; Meta-analysis; Mortality; Systematic review.

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Conflict of interest statement

ICMJE Conflict of Interest:None declared

Figures

Fig. 1
Fig. 1
Study flow diagram
Fig. 2
Fig. 2
Forest plot of 30-day mortality data.
Fig. 3
Fig. 3
Forest plot of 90-day mortality data.
See this image and copyright information in PMC

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