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Review
. 2014 Sep;3(3):R81-93.
doi: 10.1530/EC-14-0038. Epub 2014 Jun 3.

Metabolic syndrome: is equine disease comparable to what we know in humans?

Antonia Ertelt  1 , Ann-Kristin Barton  2 , Robert R Schmitz  2 , Heidrun Gehlen  2
Affiliations
Review

Metabolic syndrome: is equine disease comparable to what we know in humans?

Antonia Ertelt et al. Endocr Connect. 2014 Sep.

Abstract

This review summarizes similarities and differences between the metabolic syndromes in humans and equines, concerning the anatomy, symptoms, and pathophysiological mechanisms. In particular, it discusses the structure and distribution of adipose tissue and its specific metabolic pathways. Furthermore, this article provides insights and focuses on issues concerning laminitis in horses and cardiovascular diseases in humans, as well as their overlap.

Keywords: cardiovascular; diabetes; inflammation; metabolism; obesity.

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Figures

Figure 1
Figure 1
Horse suffering from EMS and laminitis. The horse shows distribution of fat at characteristic sites. The rear limbs are positioned forward to relieve stress from the front hooves, a condition associated with laminitis.
Figure 2
Figure 2
Lateromedial radiographic image of the right front limb of a horse showing rotation and evidence of sinking of the coffin bone.
Figure 3
Figure 3
Lateromedial radiographic image of a physiological positioned hoof with no evidence of rotation or sinking of the coffin bone.
See this image and copyright information in PMC

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