Evidence for camel-to-human transmission of MERS coronavirus
- PMID: 24896817
- DOI: 10.1056/NEJMoa1401505
Evidence for camel-to-human transmission of MERS coronavirus
Abstract
We describe the isolation and sequencing of Middle East respiratory syndrome coronavirus (MERS-CoV) obtained from a dromedary camel and from a patient who died of laboratory-confirmed MERS-CoV infection after close contact with camels that had rhinorrhea. Nasal swabs collected from the patient and from one of his nine camels were positive for MERS-CoV RNA. In addition, MERS-CoV was isolated from the patient and the camel. The full genome sequences of the two isolates were identical. Serologic data indicated that MERS-CoV was circulating in the camels but not in the patient before the human infection occurred. These data suggest that this fatal case of human MERS-CoV infection was transmitted through close contact with an infected camel.
Comment in
-
Evidence for camel-to-human transmission of MERS coronavirus.N Engl J Med. 2014 Oct 2;371(14):1360. doi: 10.1056/NEJMc1409847. N Engl J Med. 2014. PMID: 25271614 No abstract available.
-
Evidence for camel-to-human transmission of MERS coronavirus.N Engl J Med. 2014 Oct 2;371(14):1359-60. doi: 10.1056/NEJMc1409847. N Engl J Med. 2014. PMID: 25271615 No abstract available.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical