Performance of the Verigene Gram-negative blood culture assay for rapid detection of bacteria and resistance determinants
- PMID: 24899026
- PMCID: PMC4136123
- DOI: 10.1128/JCM.01099-14
Performance of the Verigene Gram-negative blood culture assay for rapid detection of bacteria and resistance determinants
Abstract
Nonduplicate blood cultures that were positive for Gram-negative bacilli (n = 125) were tested by the Verigene Gram-negative blood culture (BC-GN) assay; 117 (90.7%) isolates were members of the panel. For identification and resistance markers, the agreements with routine methods were 97.4% (114/117) and 92.3% (12/13). The BC-GN assay is a rapid and accurate tool for the detection of pathogens from blood cultures and could be integrated alongside conventional systems to enable faster patient management, but the clinical benefits should be further evaluated.
Copyright © 2014, American Society for Microbiology. All Rights Reserved.
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References
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- Tojo M, Fujita T, Ainoda Y, Nagamatsu M, Hayakawa K, Mezaki K, Sakurai A, Masui Y, Yazaki H, Takahashi H, Miyoshi-Akiyama T, Totsuka K, Ohmagari N. 2014. Evaluation of an automated rapid diagnostic assay for detection of Gram-negative bacteria and their drug-resistance genes in positive blood cultures. PLoS One. 9:e94064. 10.1371/journal.pone.0094064 - DOI - PMC - PubMed
-
- Mancini N, Infurnari L, Ghidoli N, Valzano G, Clementi N, Burioni R, Clementi M. 2014. Potential impact of a microarray-based nucleic acid assay for rapid detection of Gram-negative bacteria and resistance markers in positive blood cultures. J. Clin. Microbiol. 52:1242–1245. 10.1128/JCM.00142-14 - DOI - PMC - PubMed
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