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. 2014 Jun;20(6):590-1.
doi: 10.1038/nm.3595.

Overcoming Drug Development Bottlenecks With Repurposing: Old drugs learn new tricks

Stephen M Strittmatter  1
Affiliations

Overcoming Drug Development Bottlenecks With Repurposing: Old drugs learn new tricks

Stephen M Strittmatter. Nat Med. 2014 Jun.
No abstract available

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Conflict of interest statement

COMPETING FINANCIAL INTERESTS

The author declares no competing financial interests.

Figures

Figure 1
Figure 1
Repurposing of drugs for rapid development. Existing compounds typically have identified molecular targets and primary indications in which they have either reached approval status or been sidelined somewhere along the pipeline, for efficacy or business reasons. If compounds are made available for further research, then investigation may identify new indications for the same target or new molecular targets with separate indications. A parallel pathway to approval for a repurposed indication can be achieved more robustly by relying on prior safety and tolerability experience with the original indication.
See this image and copyright information in PMC

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