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Editorial
. 2014;13(13):2013-4.
doi: 10.4161/cc.29458. Epub 2014 Jun 5.

Targeting genetic lesions in esophageal cancer

De-Chen Lin  1 , Ming-Rong Wang  2 , H Phillip Koeffler  1
Affiliations
Editorial

Targeting genetic lesions in esophageal cancer

De-Chen Lin et al. Cell Cycle. 2014.
No abstract available

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Figures

None
Figure 1. Druggable genetic lesions in ESCC. Targets harboring gene amplification or protein overexpression are marked in red and somatic mutations in purple. Representative therapeutic agents currently in Phase I clinical trials are marked in gray, phase II in brown, phase III in blue, and FDA-approved in green. Due to space limitations, the total number of agents for each target is shown in brackets.
See this image and copyright information in PMC

Comment on

  • Genomic and molecular characterization of esophageal squamous cell carcinoma.
    Lin DC, Hao JJ, Nagata Y, Xu L, Shang L, Meng X, Sato Y, Okuno Y, Varela AM, Ding LW, Garg M, Liu LZ, Yang H, Yin D, Shi ZZ, Jiang YY, Gu WY, Gong T, Zhang Y, Xu X, Kalid O, Shacham S, Ogawa S, Wang MR, Koeffler HP. Lin DC, et al. Nat Genet. 2014 May;46(5):467-73. doi: 10.1038/ng.2935. Epub 2014 Mar 30. Nat Genet. 2014. PMID: 24686850 Free PMC article.

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