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Comment
. 2014 Jun 5;14(6):695-7.
doi: 10.1016/j.stem.2014.05.010.

Disease progression in myelodysplastic syndromes: do mesenchymal cells pave the way?

Marc H G P Raaijmakers  1
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Disease progression in myelodysplastic syndromes: do mesenchymal cells pave the way?

Marc H G P Raaijmakers. Cell Stem Cell. .
Free article

Abstract

Early events driving the initiation and evolution of neoplasms remain poorly defined but involvement of an instructive or permissive niche has been implicated. In this issue of Cell Stem Cell, Medyouf et al. (2014) provide insights into the role of the niche in myelodysplastic syndromes, the principle preleukemic disorder of the hematopoietic system.

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