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Case Reports
. 2014 May 29;19(21):20812.
doi: 10.2807/1560-7917.es2014.19.21.20812.

Transfusion-transmitted hepatitis E in Germany, 2013

D Huzly  1 , M Umhau, D Bettinger, T Cathomen, F Emmerich, P Hasselblatt, H Hengel, R Herzog, O Kappert, S Maassen, E Schorb, C Schulz-Huotari, R Thimme, R Unmüssig, J J Wenzel, M Panning
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Free article
Case Reports

Transfusion-transmitted hepatitis E in Germany, 2013

D Huzly et al. Euro Surveill. .
Free article

Abstract

The reported IgG seroprevalence against hepatitis E virus (HEV) in German blood donations is 6.8%, and HEV RNA detected in 0.08%, but documented evidence for HEV transmission is lacking. We identified two donations from a single donor containing 120 IU HEV RNA/mL plasma and 490 IU/mL. An infectious dose of 7,056 IU HEV RNA was transmitted via apheresis platelets to an immunosuppressed patient who developed chronic HEV. Further, transmission was probable in an immunocompetent child.

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