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. 2014 Apr-Jun;8(2):82-7.
doi: 10.1016/j.dsx.2014.04.023. Epub 2014 May 23.

Incidence and risk of diabetes mellitus associated with depressive symptoms in adults: evidence from longitudinal studies

Syed Shahzad Hasan  1 , Alexandra M Clavarino  2 , Abdullah A Mamun  3 , Therese Kairuz  4
Affiliations

Incidence and risk of diabetes mellitus associated with depressive symptoms in adults: evidence from longitudinal studies

Syed Shahzad Hasan et al. Diabetes Metab Syndr. 2014 Apr-Jun.

Abstract

Aims: We estimated the incidence and risk of diabetes associated with depressive symptoms using data from longitudinal studies.

Materials and methods: Databases were systematically searched for relevant studies. Incidence of diabetes is presented as cumulative incident proportion (CIP). Pooled effect sizes were calculated using random-effects model. The data were reconstructed to compute relative risk (RR).

Results: The 16 studies selected for review generated 16 datasets of which 8 studies reporting binary estimates (RR) and 8 studies reporting time-to-event estimates (hazard ratio (HR)). Both RR and HR were significant at 1.67 (95% CI: 1.30-2.15) and 1.45 (95% CI: 1.12-1.87) for incident diabetes associated with depressive symptoms.

Conclusion: Our observations revealed greater cumulative incidence of diabetes in depressed than in non depressed groups. Depression should be included among risk factors that required regular screening for diabetes.

Keywords: Adults; Depression; Diabetes; Incidence; Longitudinal.

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