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Review
. 2014 Jun;41(6):471-86.
doi: 10.1111/1346-8138.12486.

Japanese guidelines for the management of pemphigus

Committee for Guidelines for the Management of Pemphigus Disease; Masayuki Amagai, Akiko Tanikawa, Tomoko Shimizu, Takashi Hashimoto, Shigaku Ikeda, Michiko Kurosawa, Hironori Niizeki, Yumi Aoyama, Keiji Iwatsuki, Yasuo Kitajima
Review

Japanese guidelines for the management of pemphigus

Committee for Guidelines for the Management of Pemphigus Disease et al. J Dermatol. 2014 Jun.

Abstract

The Committee for Guidelines for the Management of Pemphigus was organized as one element of the Japanese Dermatological Association (JDA) and the Ministry of Health, Labour, and Welfare (MHLW) Research Project on Measures for Research Committee for Intractable Skin Disease. Pemphigus has been defined as a group of intractable autoimmune blistering diseases caused by anti-desmoglein 1 and/or anti-desmoglein 3 IgG autoantibodies by the MHLW. The diagnosis of this condition and the criteria for assessing its severity are based on suggestions from the MHLW Research Group. The clinical practice guidelines presented here are those that are currently recommended in Japan. However, symptoms and complications can vary widely among individual pemphigus patients, so not all therapies will be required to be in complete agreement with these guidelines.

Keywords: autoantibody; desmoglein; diagnosis; therapy.

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