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. 2014 Sep;76(9):1291-5.
doi: 10.1292/jvms.14-0139. Epub 2014 Jun 9.

Efficacy of Malarone(®) in dogs naturally infected with Babesia gibsoni

Aiko Iguchi  1 , Nobuyuki Shiranaga, Aya Matsuu, Yoshiaki Hikasa
Affiliations

Efficacy of Malarone(®) in dogs naturally infected with Babesia gibsoni

Aiko Iguchi et al. J Vet Med Sci. 2014 Sep.

Abstract

The efficacy of Malarone(®) alone and in combination with doxycycline (DOXY) against Babesia gibsoni infections was examined in 8 dogs. In all dogs except one treated with Malarone(®), parasitemia decreased, and anemia improved soon after initiation of treatment. However, 3 of 4 dogs treated with Malarone(®) relapsed, and relapse was inhibited in 2 of 4 dogs treated with Malarone(®) and DOXY. All relapsed dogs responded well to the second treatment, but 1 dog relapsed again and did not respond to the third treatment. Malarone(®) may be useful for acute stage of B. gibsoni infections, and at least second repeating treatment might be effective.

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Figures

Fig. 1.
Fig. 1.
Changes in PCV (○), number of PLT (■) and parasitemia (♦) in the 8 dogs. The period of Malarone® (solid line) and/or DOXY (dot line) treatment is shown as bows under the figure.
See this image and copyright information in PMC

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