Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2014 Jun 9;29(5):505-506.
doi: 10.1016/j.devcel.2014.05.016.

Directing traffic and autophagy in axonal transport

Affiliations
Comment

Directing traffic and autophagy in axonal transport

Peter J Hollenbeck. Dev Cell. .

Abstract

In this issue of Developmental Cell, Fu et al. (2014) address what determines persistent directional movement along microtubules of organelles capable of bidirectional transit. They show that retrograde axonal autophagosome transport is mediated by the scaffolding protein JIP1, which not only inhibits anterograde movement but may also promote autophagosome maturation.

PubMed Disclaimer

Comment on

References

    1. Fu MM, Holzbaur EL. J Cell Biol. 2013;202:495–508. - PMC - PubMed
    1. Fu MM, Nirschl JJ, Holzbaur ELF. Dev Cell. 2014 This issue. - PMC - PubMed
    1. Hollenbeck PJ. J Cell Biol. 1993;121:305–315. - PMC - PubMed
    1. Horiuchi D, Barkus RV, Pilling AD, Gassman A, Saxton WM. Curr Biol. 2005;15:2137–2141. - PMC - PubMed
    1. Maday S, Wallace KE, Holzbaur EL. J Cell Biol. 2012;196:407–417. - PMC - PubMed

MeSH terms

LinkOut - more resources