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Review
. 2014 Jul;15(7):466-81.
doi: 10.1038/nrn3766. Epub 2014 Jun 11.

Grid cells and cortical representation

Edvard I Moser  1 , Yasser Roudi  1 , Menno P Witter  1 , Clifford Kentros  2 , Tobias Bonhoeffer  3 , May-Britt Moser  1
Affiliations
Review

Grid cells and cortical representation

Edvard I Moser et al. Nat Rev Neurosci. 2014 Jul.

Abstract

One of the grand challenges in neuroscience is to comprehend neural computation in the association cortices, the parts of the cortex that have shown the largest expansion and differentiation during mammalian evolution and that are thought to contribute profoundly to the emergence of advanced cognition in humans. In this Review, we use grid cells in the medial entorhinal cortex as a gateway to understand network computation at a stage of cortical processing in which firing patterns are shaped not primarily by incoming sensory signals but to a large extent by the intrinsic properties of the local circuit.

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