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Practice Guideline
. 2014 Aug;63(8):1210-28.
doi: 10.1136/gutjnl-2013-306578. Epub 2014 Jun 10.

Diagnosis and management of adult coeliac disease: guidelines from the British Society of Gastroenterology

Jonas F Ludvigsson  1 , Julio C Bai  2 , Federico Biagi  3 , Timothy R Card  4 , Carolina Ciacci  5 , Paul J Ciclitira  6 , Peter H R Green  7 , Marios Hadjivassiliou  8 , Anne Holdoway  9 , David A van Heel  10 , Katri Kaukinen  11 , Daniel A Leffler  12 , Jonathan N Leonard  13 , Knut E A Lundin  14 , Norma McGough  15 , Mike Davidson  16 , Joseph A Murray  17 , Gillian L Swift  18 , Marjorie M Walker  19 , Fabiana Zingone  5 , David S Sanders  20 ; BSG Coeliac Disease Guidelines Development Group; British Society of Gastroenterology
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Free PMC article
Practice Guideline

Diagnosis and management of adult coeliac disease: guidelines from the British Society of Gastroenterology

Jonas F Ludvigsson et al. Gut. 2014 Aug.
Free PMC article

Abstract

A multidisciplinary panel of 18 physicians and 3 non-physicians from eight countries (Sweden, UK, Argentina, Australia, Italy, Finland, Norway and the USA) reviewed the literature on diagnosis and management of adult coeliac disease (CD). This paper presents the recommendations of the British Society of Gastroenterology. Areas of controversies were explored through phone meetings and web surveys. Nine working groups examined the following areas of CD diagnosis and management: classification of CD; genetics and immunology; diagnostics; serology and endoscopy; follow-up; gluten-free diet; refractory CD and malignancies; quality of life; novel treatments; patient support; and screening for CD.

Keywords: Coeliac Disease; Gluten; Gluten Free Diet; Small Bowel Disease.

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Figures

Figure 1
Figure 1
Relationship between villous height and crypt depth. CD, crypt depth; IEL, intraepithelial lymphocyte; LD, lymphocytic duodenosis; PVA, partial villous atrophy; TVA, total villous atrophy; VH, villous height. The dots represent IELs.
Figure 2
Figure 2
Investigation of the patient with non-responsive coeliac disease (NRCD). Based on a figure by Mooney et al. FODMAPs, fermentable oligosaccharides, disaccharides, monosaccharides, and polyols; GI, gastrointestinal; HLA, human leucocyte antigen; RCD, refractory coeliac disease; SIBO, small intestine bacterial overgrowth.
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References

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