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. 2013 Feb;7(3):132-5.
doi: 10.1159/000356265. Epub 2014 Feb 10.

Use of BioGlue Surgical Adhesive in Hypospadias Repair

Stanislav Kocherov  1 , Genady Lev  1 , Boris Chertin  1
Affiliations

Use of BioGlue Surgical Adhesive in Hypospadias Repair

Stanislav Kocherov et al. Curr Urol. 2013 Feb.

Abstract

Purpose: To prospectively evaluate the efficacy of albumin glutaraldehyde tissue adhesive (BioGlue) in the surgical treatment of patients with hypospadias.

Materials and methods: Two groups of 20 patients each who underwent hypospadias repair were included in the study. In the first group we utilized BioGlue as an additional protective layer to the suture line of the neo-urethra, while patients in the second group were operated on utilizing a routine surgical technique.

Results: There were no statistical differences between patients from the 2 groups in terms of surgical complications. Urethrocutaneous fistula was revealed in 4 (20%) patients after repair with BioGlue and in 3 (15%) patients from the control group (p = 0.686), suture line breakdown in 4 (20%) and in 1 (5%) patients (p = 0.478), meatal stenosis in 1 (5%) and in 1 (5%) patient (p = 1). Furthermore more patients in the BioGlue group (n = 12, 60%) demonstrated poor cosmetic results compared to the control group where most patients - 19 (95%) had acceptable cosmetic outcomes (p = 0.007).

Conclusions: Our data showed no benefits of BioGlue use in hypospadias repair.

Keywords: BioGlue; Hypospadias; Hypospadias repair; Urethrocutaneous fstula.

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References

    1. Mouriquand PD, Persad R, Sharma S. Hypospadias repair: Current principles and procedures. Br J Urol. 1995;76(suppl 3):9–22. - PubMed
    1. Smith ED. The history of hypospadias. Pediatr Surg Int. 1997;21:81–85. - PubMed
    1. Thiersch C. Uber die entstehungswise and operative behandlung der epispadie. Arch Heitkunde. 1869;10:20–25.
    1. Duplay S. De l'hypospade périnéoscrotal et de son traitement chirurgical. Arch General Med. 1874;1:613–657.
    1. Hafez AT, Helmy T. Tabularized incised plate repair for penoscrotal hypospadias: role of surgeon's experience. Urology. 2012;79:425–427. - PubMed

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