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. 2014 Nov-Dec;35(6):e406-12.
doi: 10.1097/BCR.0000000000000026.

The role of seizure disorders in burn injury and outcome in Sub-Saharan Africa

Laura P Boschini  1 , Anna F Tyson, Jonathan C Samuel, Claire E Kendig, Stephano Mjuweni, Carlos Varela, Bruce A Cairns, Anthony G Charles
Affiliations

The role of seizure disorders in burn injury and outcome in Sub-Saharan Africa

Laura P Boschini et al. J Burn Care Res. 2014 Nov-Dec.

Abstract

Patients with epilepsy have higher incidence and severity of burn injury. Few studies describe the association between epilepsy and burns in low-income settings, where epilepsy burden is highest. The authors compared patients with and without seizure disorder in a burn unit in Lilongwe, Malawi. The authors conducted a retrospective study of patients admitted to the Kamuzu Central Hospital burn ward from July 2011 to December 2012. Descriptive analysis of patient characteristics and unadjusted and adjusted analyses of risk factors for mortality were conducted for patients with and without seizure disorder. Prevalence of seizure disorder was 10.7% in the study population. Adults with burns were more likely to have seizure disorder than children. Flame injury was most common in patients with seizure disorder, whereas scalds predominated among patients without seizure disorder. Whereas mortality did not differ between the groups, mean length of stay was longer for patients with seizure disorder, 42.1 days vs 21.6 days. Seizure disorder continues to be a significant risk factor for burn injury in adults in Malawi. Efforts to mitigate epilepsy will likely lead to significant decreases in burns among adults in Sub-Saharan Africa and must be included in an overall burn prevention strategy in our environment.

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Figures

Figure 1
Figure 1. Percentage of Children and Adults*, Stratified by Seizure Disorder Status
*Pediatric (0-15 years), Adult (>15 years)
Figure 2
Figure 2. Percentage of Burn Mechanisms by Children and Adults*, Stratified by Seizure Disorder Status
*Pediatric (0-15 years), Adult (>15 years)
See this image and copyright information in PMC

References

    1. Lozano R, Naghavi M, Foreman K, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380(9859):2095–128. - PMC - PubMed
    1. Peck MD. Epidemiology of burns throughout the world. Part I: Distribution and risk factors. Burns. 2011;37(7):1087–100. - PubMed
    1. Murray CJL, Vos T, Lozano R, et al. Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380:2197–223. - PubMed
    1. World Health Organization. Atlas: Epilepsy Care in the World. Geneva: World Health Organization; 2005.
    1. Newton CR, Garcia HH. Epilepsy in poor regions of the world. Lancet. 2012;380(9848):1193–201. - PubMed

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