An unexpected role: UVA-induced release of nitric oxide from skin may have unexpected health benefits
- PMID: 24924758
- DOI: 10.1038/jid.2014.33
An unexpected role: UVA-induced release of nitric oxide from skin may have unexpected health benefits
Abstract
UVR has deleterious and beneficial effects on human health. In this issue, Liu et al. (2014) show that UVA decreases blood pressure and increases blood flow and heart rate in humans, which is beneficial to the cardiovascular system. This is likely mediated by UVA causing release of nitric oxide (NO) from skin stores. This mediator may have additional effects on human health.
Comment on
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UVA irradiation of human skin vasodilates arterial vasculature and lowers blood pressure independently of nitric oxide synthase.J Invest Dermatol. 2014 Jul;134(7):1839-1846. doi: 10.1038/jid.2014.27. Epub 2014 Jan 20. J Invest Dermatol. 2014. PMID: 24445737 Clinical Trial.
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