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. 2014 Mar;19(1):45-8.
doi: 10.6065/apem.2014.19.1.45. Epub 2014 Mar 31.

Giant juvenile fibroadenoma of the breast: a case report and brief literature review

Bong Sup Song  1 , Eun-Kyu Kim  2 , Hyesil Seol  3 , Ju-Hee Seo  1 , Jun Ah Lee  1 , Dong Ho Kim  1 , Jung Sub Lim  1
Affiliations

Giant juvenile fibroadenoma of the breast: a case report and brief literature review

Bong Sup Song et al. Ann Pediatr Endocrinol Metab. 2014 Mar.

Abstract

A girl (age, 12 years 11 months) consulted the pediatric endocrinology clinic because of a rapidly growing right breast mass over 13 cm observed during the preceding 3 months. A surgical excision was performed, and the mass was diagnosed as a giant juvenile fibroadenoma. Giant juvenile fibroadenomas are rare, usually occurring between 10 and 18 years of age, and characterized by massive and rapid enlargement of an encapsulated mass. The etiology is believed to be an end-organ hypersensitivity to normal levels of estrogen. We report a case of giant juvenile fibroadenoma and present a review of the diagnostic workup and management of a large breast tumor during adolescence.

Keywords: Adolescent; Breast; Fibroadenoma; Juvenile gigantomastia.

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Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1
Fig. 1
Gross appearance of the right breast. The overlying skin has a shiny, tense appearance with vein engorgement.
Fig. 2
Fig. 2
An ultrasonogram showing a well capsulated giant homogeneous isoechoic mass occupying entire right breast.
Fig. 3
Fig. 3
The tumor is covered with a capsule and is elastic hard. The cut surface is solid and has a yellowish white tan color.
Fig. 4
Fig. 4
The tumor shows pericanalicular pattern growth, uniformly increased stromal cellularity, and epithelial proliferation (H&E, ×40).
See this image and copyright information in PMC

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