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Editorial
. 2014 Aug;12(8):901-4.
doi: 10.1586/14787210.2014.929498. Epub 2014 Jun 13.

Control of Japanese encephalitis in Asia: the time is now

Affiliations
Editorial

Control of Japanese encephalitis in Asia: the time is now

Susan Hills et al. Expert Rev Anti Infect Ther. 2014 Aug.

Abstract

Japanese encephalitis (JE) virus is the most common vaccine-preventable cause of encephalitis in Asia. Recent progress in the development and availability of improved JE vaccines has revitalized the prospects for JE control. There now are a number of safe and effective vaccines, two WHO prequalified vaccines available for pediatric use, at least one vaccine considered affordable for use in lower income countries, and a GAVI Alliance commitment to provide financial support to eligible countries for campaigns for children aged 9 months through 14 years. While challenges remain, this tremendous progress means there is a better opportunity than at any time in the past to prevent the substantial morbidity and mortality from this disease.

Keywords: Japanese encephalitis vaccine; epidemiology; prevention and control.

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Conflict of interest statement

Financial & competing interests disclosure

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties. The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.

No writing assistance was utilized in the production of this manuscript.

References

    1. Campbell GL, Hills SL, Fischer M, et al. Estimated global incidence of Japanese encephalitis: a systematic review. Bull World Health Organ. 2011;89:766–774E. - PMC - PubMed
    1. World Health Organization. Japanese encephalitis vaccines. Wkly Epidemiol Rec. 2006;81:325–40.
    1. PATH. [Last accessed 21 April 2014];Japanese encephalitis morbidity, mortality, and disability: reduction and control by 2015. Available from: www.path.org/vaccineresources/files/JE_Reduction_and_Control_by_2015.pdf.
    1. Kumar R, Tripathi P, Rizvi A. Effectiveness of one dose of SA 14-14-2 vaccine against Japanese encephalitis. N Engl J Med. 2009;360:1465–6. - PubMed
    1. Gatchalian S, Yao Y, Zhou B, et al. Comparison of the immunogenicity and safety of measles vaccine administered alone or with live, attenuated Japanese encephalitis SA 14-14-2 vaccine in Philippine infants. Vaccine. 2008;26:2234–41. - PubMed

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