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. 2014 Jul:60:121-30.
doi: 10.1016/j.neuropsychologia.2014.06.003. Epub 2014 Jun 13.

Verbal learning and memory in agenesis of the corpus callosum

Roger L Erickson  1 , Lynn K Paul  2 , Warren S Brown  3
Affiliations

Verbal learning and memory in agenesis of the corpus callosum

Roger L Erickson et al. Neuropsychologia. 2014 Jul.

Abstract

The role of interhemispheric interactions in the encoding, retention, and retrieval of verbal memory can be clarified by assessing individuals with complete or partial agenesis of the corpus callosum (AgCC), but who have normal intelligence. This study assessed verbal learning and memory in AgCC using the California Verbal Learning Test-Second Edition (CVLT-II). Twenty-six individuals with AgCC were compared to 24 matched controls on CVLT-II measures, as well as Donders׳ four CVLT-II factors (i.e., Attention Span, Learning Efficiency, Delayed Memory, and Inaccurate Memory). Individuals with AgCC performed significantly below healthy controls on the Delayed Memory factor, confirmed by significant deficits in short and long delayed free recall and cued recall. They also performed less well in original learning. Deficient performance by individuals with AgCC during learning trials, as well as deficits in all forms of delayed memory, suggest that the corpus callosum facilitates interhemispheric elaboration and encoding of verbal information.

Keywords: Corpus callosum; Encoding; Verbal learning; Verbal memory.

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Figures

Fig. 1
Fig. 1
Average factor scores for AgCC and control groups on each of Donders’ four CVLT factors (AS=Attention Span, LE=Learning Efficiency, DM=Delayed Memory, and IM=Inaccurate Memory).
Fig. 2
Fig. 2
Average correct responses on learning Trials 1–5 for AgCC and control groups: (A) raw scores; (B) standard scores.
See this image and copyright information in PMC

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