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Review
. 2014 May 24:4:15.
doi: 10.1186/2110-5820-4-15. eCollection 2014.

Extracorporeal life support for patients with acute respiratory distress syndrome: report of a Consensus Conference

Christian Richard  1 , Laurent Argaud  2 , Alice Blet  3 , Thierry Boulain  4 , Laetitia Contentin  5 , Agnès Dechartres  6 , Jean-Marc Dejode  7 , Laurence Donetti  8 , Muriel Fartoukh  9 , Dominique Fletcher  10 , Khaldoun Kuteifan  11 , Sigismond Lasocki  12 , Jean-Michel Liet  7 , Anne-Claire Lukaszewicz  13 , Hervé Mal  14 , Eric Maury  15 , David Osman  16 , Hervé Outin  17 , Jean-Christophe Richard  18 , Francis Schneider  19 , Fabienne Tamion  20
Affiliations
Review

Extracorporeal life support for patients with acute respiratory distress syndrome: report of a Consensus Conference

Christian Richard et al. Ann Intensive Care. .

Abstract

The influenza H1N1 epidemics in 2009 led a substantial number of people to develop severe acute respiratory distress syndrome and refractory hypoxemia. In these patients, extracorporeal membrane oxygenation was used as rescue oxygenation therapy. Several randomized clinical trials and observational studies suggested that extracorporeal membrane oxygenation associated with protective mechanical ventilation could improve outcome, but its efficacy remains uncertain. Organized by the Société de Réanimation de Langue Française (SRLF) in conjunction with the Société Française d'Anesthésie et de Réanimation (SFAR), the Société de Pneumologie de Langue Française (SPLF), the Groupe Francophone de Réanimation et d'Urgences Pédiatriques (GFRUP), the Société Française de Perfusion (SOFRAPERF), the Société Française de Chirurgie Thoracique et Cardiovasculaire (SFCTV) et the Sociedad Española de Medecina Intensiva Critica y Unidades Coronarias (SEMICYUC), a Consensus Conference was held in December 2013 and a jury of 13 members wrote 65 recommendations to answer the five following questions regarding the place of extracorporeal life support for patients with acute respiratory distress syndrome: 1) What are the available techniques?; 2) Which patients could benefit from extracorporeal life support?; 3) How to perform extracorporeal life support?; 4) How and when to stop extracorporeal life support?; 5) Which organization should be recommended? To write the recommendations, evidence-based medicine (GRADE method), expert panel opinions, and shared decisions taken by all the thirteen members of the jury of the Consensus Conference were taken into account.

Keywords: Acute respiratory distress syndrome; Extracorporeal CO2 removal; Extracorporeal life support; Extracorporeal membrane oxygenation; Protective ventilation.

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