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Comment
. 2014 Jun 16;24(12):R560-R562.
doi: 10.1016/j.cub.2014.05.013.

Autophagy: close contact keeps out the uninvited

Hitoshi Nakatogawa  1 , Yoshinori Ohsumi  2
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Comment

Autophagy: close contact keeps out the uninvited

Hitoshi Nakatogawa et al. Curr Biol. .
Free article

Abstract

In selective autophagy, autophagosomes sequester specific targets to be degraded in lysosomes/vacuoles. A new study now provides critical insights into the mechanism by which the autophagosomal membrane closely sticks to the target to avoid incorporating material that should not be degraded.

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