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. 2014 Aug;79(4):428-31.
doi: 10.1016/j.diagmicrobio.2014.05.004. Epub 2014 May 17.

Experimental treatment of Curvularia infection

Katihuska Paredes  1 , Javier Capilla  1 , Deanna A Sutton  2 , Emilio Mayayo  3 , Annette W Fothergill  2 , Josep Guarro  4
Affiliations

Experimental treatment of Curvularia infection

Katihuska Paredes et al. Diagn Microbiol Infect Dis. 2014 Aug.

Abstract

We have evaluated the efficacy of amphotericin B, posaconazole, and voriconazole in immunosuppressed murine models of disseminated infection by Curvularia spicifera and Curvularia hawaiiensis. The 3 antifungals improved survival of mice in comparison to controls; however, only the 2 azoles were able to reduce significantly the fungal load.

Keywords: Animal model; Bipolaris hawaiiensis; Bipolaris spicifera; Curvularia; Fungal infection.

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